Background: The integration of genetic code from RNA viruses into host DNA, once thought to be a rare or even impossible phenomenon, is now recognized as probable. The Long Interspersed Nuclear Element (LINE)-1 mediated mechanism of insertion implies that many viral RNAs (apart from retroviral) can be reverse transcribed and then stably incorporated into DNA. Recombination between exogenous non-retroviral RNA and endogenous retroviral sequences that leads to reverse transcription and finally integration of the resulting cDNA into the host genome has been described. Recent data demonstrate that SARS-CoV-2 RNA sequences can be transcribed into DNA and may be actively integrated into the genome of affected human cells, mediated by retrotransposons. In some SARS-CoV-2 infected patient specimens, there is evidence for a large fraction SARS-CoV-2 sequence integration and subsequent generation of SARS-CoV-2 human chimeric transcripts.
Results: In this review, the potential role of mobile genetic elements in the etiopathogenesis of neurological, cardiovascular, immunological, and oncological disease and the possibilities of human DNA interference by SARS-CoV-2 infection and vaccination are explored. Vulnerable germ line cells, cancer cells, and neurons can presumably all be targets for anomalous mRNA integration, especially in aging cells that show increased LINE-1 activity compared to younger cells. The mRNA coding for the SARS-CoV-2 spike glycoprotein in the vaccines has been carefully designed to increase stability and efficiency of spike protein translation, thus avoiding normal mRNA degradation pathways. This may increase the potential for genomic integration. If this should be the case, the predicted consequences pose serious potential risks to human health that are in need of clarification.
Conclusion: Further toxicity evaluations are urgently needed to quantify potential emergence of interference with canonical DNA processes that could detrimentally impact the mRNA-vaccinated population.
So what have they discovered here? It has been hypothesized for almost a year that mRNA injections do indeed reverse transcriptase into the human DNA genome. What this study is hypothesizing and showing data to support is that the RNA viruses such as covid integrating into DNA is “probable”. There is a portion of RNA called the LINE-1 insertion spot that can reverse transcribe into DNA.
Think of it as a key that fits into a keyhole. The LINE-1 is the key, the human DNA sequence has a keyhole that is available for them to line up. There is “evidence that large fractions of the SARS COV-2 genetic sequence integration with subsequent generation (creation) of SARS COV-2 human chimeric transcripts”.
What this implies and hypothesizes is that when the genetic sequence integrates and creates a new DNA sequence, it is a non-natural duplication considered chimeric (which it is illegal to do a chimera study just FYI). Chimera is a genetically altered version of something to create an alternate form of the original thing. It is unethical and illegal to create a chimera.
The consequences of this LINE-1 insertion into the human DNA have been shown to have cardiac, neurological, immunological, and oncology consequences. As in, heart problems, brain problems, immune problems, and cancer problems. Furthermore, they found that germ line cells, cancer cells, and neurons all have a greater affinity for this LINE-1 sequence to alter DNA in those areas and need further study.
Why is the MRNA vaccine doing this when other virus injections do not? The spike protein in the MRNA vaccines was DESIGNED to be super stable to avoid degrading. It does not break down via normal pathways in the body. It is designed to stay intact for far longer than it should be. This area needs further study to determine what long term effects this is causing in the body. We need to understand the role of this vaccine integrating into the human genome so we can figure out what the risks are long term to the vaccinated.
Dr. McCullough was speaking last week about this study and his concerns for permanent DNA alterations being able to be passed along to offspring. We do not know what the long term impact is yet. But each study adds more to the plate of what this injection was designed to do, and it was not anything good.
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