That part where they admit that mRNA lipid nanoparticles edit cells and DNA

 

In an article meant to proclaim the wonderful achievements of mRNA and lipid nanoparticles, they also admit the damage they can do. I will bold the portions of this to pay particular attention to. Because if mRNA and LNP’s can be designed to do this, what was the covid shot payload designed to do?

“The new advance involves a single injection and uses antibodies to target the payload to its intended destination. And it makes its cellular or genetic modifications directly in the body without the need for cell extraction. (Where was the designed destination for the payload of the covid shot? We do not know.) 

The researchers developed two payloads: one that edited a mutation for sickle cell disease, and another that selectively killed HSCs, which would eliminate the need for chemotherapy before HSC transplantion. If the therapies can be successfully adapted to people, this approach “will actually make gene therapy affordable, not only to our patients but also to our health care system,” says Hamideh Parhiz, a biotechnologist at the University of Pennsylvania, who co-led the research. (There is that payload word again…..they designed a mRNA/LNP payload to destroy stem cells! 

Again I ask…..what is the payload of the covid shot? HSC’s are hematopoietic stem cells, AKA stem cells in your bone marrow. When someone has a bone marrow transplant, they wipe your entire immune system with chemo, then transplant new stem cells into the body. This is used for leukemia, multiple myeloma, blood and marrow cancers. They are now proclaiming that they can select certain stem cells to die with a payload of mRNA and LNPs. So they could kill all of your HSC’s if they wanted to). 

The researchers designed the lipid nanoparticles to target HSCs using an antibody that binds to the protein CD117, which is commonly found on these cells’ surface. After confirming that the nanoparticles were breaking through into about half of blood cells, they loaded the antibody-coated nanoparticles with an mRNA encoding a protein that induces cell death. Although the nanoparticles killed HSCs, the researchers discovered some off-target effects, so they added tiny bits of noncoding RNA that kept the protein from killing other cells. “That’s when we got success,” Parhiz says. 

In another experiment, the researchers stuffed their nanoparticles with an mRNA sequence that produces a gene editor when it enters the cell. The editor targets a mutation in hemoglobin causing sickle cell disease.

This is terrifying:

Parhiz and her colleagues are working on fine-tuning the approach and testing it further in animals to get a better understanding of how efficiently it edits intended genes and how well it targets HSCs. (Further study of how they can gene edit and delete us in the name of good, when it can be used as something very bad.)