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Monday, April 27, 2020

HIGH DOSAGE VITAMIN C DELIVERED INTRAVENOUSLY, KILLS CANCER AND CORONAVIRUS


From Oncology Nurse Advisor:
High-dose vitamin C causes cancer cells to die in a cell culture model. These experiments revealed the mechanism of action by which vitamin C achieves this.1 As vitamin C breaks down, it generates hydrogen peroxide. 
Hydrogen peroxide is a reactive oxygen species that can cause cellular and DNA damage. Tumor cells are less able to remove hydrogen peroxide due to low levels of catalase, an enzyme that removes hydrogen peroxide. 
“In this paper we demonstrate that cancer cells are much less efficient in removing hydrogen peroxide than normal cells. Thus, cancer cells are much more prone to damage and death from a high amount of hydrogen peroxide,” said senior author Garry Buettner, PhD, a professor of radiation oncology and a member of Holden Comprehensive Cancer Center at the University of Iowa in Iowa City, Iowa. 
“This explains how the very, very high levels of vitamin C used in our clinical trials do not affect normal tissue, but can be damaging to tumor tissue.” 
Intravenous delivery of vitamin C can bypass the gut metabolism and excretion pathway, resulting in serum levels that are 100 to 500 times higher than serum levels after oral ingestion. At this higher serum level, vitamin C could cause the selective death of cancer cells over healthy cells.
AND THEN THERE'S THIS FROM HARVARD.EDU:
The idea that high-dose IV vitamin C might help in overwhelming infections is not new. A 2017 study found that high-dose IV vitamin C treatment (along with thiamine and corticosteroids) appeared to prevent deaths among people with sepsis, a form of overwhelming infection causing dangerously low blood pressure and organ failure. 
Another study published last year assessed the effect of high-dose vitamin C infusions among patients with severe infections who had sepsis and acute respiratory distress syndrome (ARDS), in which the lungs fill with fluid. 
While the study's main measures of improvement did not improve within the first four days of vitamin C therapy, there was a lower death rate at 28 days among treated patients. 
Though neither of these studies looked at vitamin C use in patients with COVID-19, the vitamin therapy was specifically given for sepsis and ARDS, and these are the most common conditions leading to intensive care unit admission, ventilator support, or death among those with severe COVID-19 infections.

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