Click on MZ362874.1 and it points to a Moderna HIV vaccine patent filed March 13th, 2020 where Anthony Fauci is an author. The patent was published on Patent: US (PCT/US2020/022710)-A 13-MAR-2020
The NIH makes note of this on their website.
So how on earth did this get into this SARs-CoV-2 vaccine and what is gp145 doing covalently linked to spike? That doesn’t make any sense unless there is an IRES element between them? IRES = Internal Ribosomal Entry Sites. These enable polycistronic sequences to be translated in parallel from two promoters. Think of IRES an an internal promoter that recruits its own Ribosome for parallel translation of proteins from a single long mRNA.
These do not have a consensus sequence we can look for. IRES elements are difficult to predict from sequence alone and require biological validation.
There is another more likely hypothesis given this unexpected sequence is from a Moderna patent. It could be a contaminant plasmid in Moderna’s IVT reaction which template switches and makes chimeric transcripts with two different vaccine targets? Template switching occurs when the T7 Polymerase is transcribing a template and then hops onto another template and makes chimeric RNA. This can happen in cis or in trans. Cis template switching is often called loopback template switching and occur more often when there are palindromic sequences on the RNA (Figure 1A). Trans Template switching occurs when two different DNAs have similar short sequences that terminal end of an RNA can decide to re-prime off two different templates.
Moderna having the highest GC content in their spike codon optimization was notorious for template switching. They published a paper in 2023 showcasing their mutated T7 polymerase designed to eliminate this artifact. In doing so they lifted the veil on how much of this template switching their normal IVT process generated. See Figure 4 below. Those wildtype (WT) smears are all template switches. The mutated polymerase eliminates this. This is the source of the mess in BlotGate. The Poor RIN numbers and smeary gels; those are template switch artifacts. I just never expected to see another Moderna HIV sequence with Anthony Fauci’s name on it, in the C19 vaccines!
I recall some people claiming to test positive for HIV post C19 vaccination. I don’t know the details of those tests to know if this is playing a role but it has no business being in this vaccine sequence if it in fact was never disclosed (the plasmid DNA wasn’t but this HIV sequence might exist in the sequence they gave the regulators).
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