Thursday, September 28, 2023

Lack of Hydroxychloroquine was the major contributor to covid deaths

The study, ‘Access to Hydroxychloroquine Is Associated with Reduced COVID-19 Mortality: A Cross-Country Analysis’, which was published yesterday in the Public Health Policy Research section of the IPAK PHPI open-access journal Science, Public Health Policy & the Law, controlled for other variables like obesity, urbanisation, age, healthcare infrastructure, and policy responses such as lockdowns and travel restrictions. 

A key finding of the studies included was a robust negative relationship between access to HCQ and covid-19 fatalities. Countries that restricted access to hydroxychloroquine had higher fatalities. The analysis model resulted in an estimate that around 520,000 fatalities could have been avoided if HCQ had been made widely available in countries where it was restricted. 

The study also found that obesity, older populations, fewer hospital beds, and less sunshine were associated with higher rates of infection and fatalities.

In contrast to these factors, which were significant across multiple models, national lockdowns were never significantly associated with lowered mortality rates, and local lockdowns were only significantly associated with lowered mortality rates in one model. 

The study therefore found that policies like lockdowns, travel restrictions, and mask mandates were generally not associated with a reduction in fatalities. PCR testing was, positively associated with reported infections, but not with fatalities, which the authors attribute to the high false positive rate of the use of non-quantitative PCR testing to assess covid-19 diagnostic status. 

A strong point in the study’s design is the author’s address of the issue of endogeneity. The authors used malaria prevalence as an instrumental variable for HCQ availability and found the result was robust and not due to confounding variables. Endogeneity in this context refers to the potential problem that the relationship between HCQ availability and covid-19 fatalities might be confounded by unobserved variables or reverse causality. The authors found that endogeneity was not an issue for the relationship between HCQ and fatalities. 

Over 500,000 deaths could have been prevented. When you combine the HCQ studies with the Ivermectin studies…….the ability to prevent death was there in 2020. We didn’t use the tools.


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